Norfloxacin is used for:
Treating bacterial infections.
Norfloxacin is a fluoroquinolone antibiotic. It works by killing sensitive bacteria.
Do NOT use norfloxacin if:
- you are allergic to any ingredient in norfloxacin or to any other fluoroquinolone antibiotic (eg, levofloxacin)
- you have inflammation of a tendon (tendonitis) or a history of ruptured tendon caused by norfloxacin or another fluoroquinolone (eg, levofloxacin)
- you have a history of myasthenia gravis
- you are taking certain antiarrhythmic medicines (eg, amiodarone, procainamide, quinidine, sotalol) or nitrofurantoin
Contact your doctor or health care provider right away if any of these apply to you.
Before using norfloxacin:
Some medical conditions may interact with norfloxacin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a stomach infection, liver problems, brain or nervous system problems, muscle problems (eg, myasthenia gravis), increased pressure in the brain, Alzheimer disease, brain blood vessel problems, or a history of seizures
- if you have a history of severe or persistent diarrhea, skin sensitivity to the sun, a recent heart attack, blood problems (eg, anemia, hemolysis), or glucose-6-phosphate dehydrogenase (G6PD) problems
- if you have a personal or family history of irregular heartbeat (eg, QT prolongation), heart problems (eg, slow heartbeat), or low blood potassium levels
- if you have a history of joint or tendon problems; rheumatoid arthritis; kidney problems or decreased kidney function; or a heart, kidney, or lung transplant
- if you take a corticosteroid (eg, prednisone) or participate in strenuous physical work or exercise
Some MEDICINES MAY INTERACT with norfloxacin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antiarrhythmics (eg, amiodarone, disopyramide, dofetilide, quinidine , sotalol), cisapride, diuretics (eg, furosemide, hydrochlorothiazide), macrolide or ketolide antibiotics (eg, erythromycin, telithromycin), medicines for mental or mood disorders, medicines that may affect your heartbeat, phenothiazines (eg, chlorpromazine), or tricyclic antidepressants (eg, amitriptyline) because the risk of serious side effects, including irregular heartbeat and other heart problems, may be increased. Check with your doctor or pharmacist if you are unsure if any of your medicines may affect your heartbeat
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of side effects, such as seizures, may be increased
- Corticosteroids (eg, prednisone) because the risk of tendon damage may be increased
- Probenecid because it may increase the risk of norfloxacin's side effects
- Nitrofurantoin because it may decrease norfloxacin's effectiveness
- Anticoagulants (eg, warfarin), caffeine, clozapine, cyclosporine, methotrexate, ropinirole, serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, venlafaxine), sulfonylureas (eg, glyburide), tacrine, theophyllines, or tizanidine because the risk of their side effects may be increased by norfloxacin
- Live vaccines or mycophenolate because their effectiveness may be decreased by norfloxacin
This may not be a complete list of all interactions that may occur. Ask your health care provider if norfloxacin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.